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Search for "directed ortho/remote metalation" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.
A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines
Beilstein J. Org. Chem. 2017, 13, 1564–1571, doi:10.3762/bjoc.13.156
- cytotoxicity against the HL-60 tumor cell line. Keywords: directed ortho/remote metalation; Eaton’s reagent; isoquinolines; Suzuki cross-coupling; Introduction Benzylisoquinoline alkaloids represent a very large group of plant secondary metabolites, which includes about 2,500 known structures. Besides simple
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